| Название | Игры |
||
| S-Tribute | 3 | ||
| Saboteur | 2 | ||
| SaGa | 6 | ||
| Saints Row | 2 | ||
| Sakura | 2 | ||
| Sakura MMO | 3 | ||
| Sakura Succubus | 3 | ||
| Salt | 2 | ||
| Sam & Max | 3 | ||
| Samurai Aces | 3 | ||
| Samurai Shodown | 3 | ||
| Samurai Warriors | 4 | ||
| Sausage | 2 | ||
| Science Adventure | 7 | ||
| Scott Pilgrim | 2 | ||
| Scribblenauts | 5 | ||
| SD Gundam G Generation | 2 | ||
| Season Match | 2 | ||
| SEGA AGES | 13 | ||
| Sega All-Stars | 2 | ||
| SEGA Classics | 16 | ||
| Senran Kagura | 5 | ||
| Sense | 2 | ||
| Serial Cleaner | 2 | ||
| Serious Sam | 2 | ||
| Shadowrun | 4 | ||
| Shantae | 10 | ||
| Sherlock Holmes | 3 | ||
| Shin Megami Tensei | 2 | ||
| Shinobi | 4 | ||
| Shovel Knight | 5 | ||
| Shred | 2 | ||
| Skautfold | 2 | ||
| Skies | 2 | ||
| Sky Force | 2 | ||
| Skylanders | 11 | ||
| Smite | 2 | ||
| Smoots | 2 | ||
| Sniper Elite | 6 | ||
| SNK | 2 | ||
| Snoopy | 2 | ||
| Sonic | 29 | ||
| South Park | 3 | ||
| Space Invaders | 2 | ||
| Sparkle (10tons Ltd) | 2 | ||
| Spelunky | 2 | ||
| Spider-Man | 3 | ||
| Spirit Hunter | 3 | ||
| SpongeBob SquarePants | 8 | ||
| Spot The Difference | 2 | ||
